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Scientific Activity

MAIN RESEARCH AREAS
 
CARDIOLOGY:
 
• interventional treatment of acute coronary syndromes – the use of new diagnostic and therapeutic methods, clinical and metabolic diagnostic markers, management optimization, long-term follow-up;
• comprehensive qualification of heart failure patients for further treatment, based on the expertise of a multi-specialty team (cardiologist, cardiac surgeon, transplantologist, nephrologist, diabetologist); long-term follow-up, cardiac transplant vasculopathy;
• the importance of revascularisation of the heart muscle with preserved vitality in patients with severe ischaemic heart failure, with a view to develop an algorithm of management in this group of patients;
• the use of resynchronisation therapy in selected patients with advanced heart failure, assessment of the implantation techniques of resynchronizing devices, and new indications for biventricular stimulation;
• search for optimal treatment methods in patients with severe pulmonary hypertension of various etiology; long-term prognosis in patients with heart failure, depending on haemodynamic parameters in the pulmonary bed;
• the first in Poland programme of hybrid treatment (MIDCAB + PCI with DES) in patients with multi-vessel coronary disease, with assessment of clinical events and angiographic follow-up at 12 months;
• assessment of sudden cardiac death risk with the use of invasive and non-invasive methods;
• the use of radiofrequency ablation in the treatment of patients with heart rhythm disorders;
• optimisation of therapeutic methods in patients with aortic disease and mitral regurgitation;
• comprehensive angioplasty services, including carotid, vertebral, renal and limb arteries;
• percutaneous interventional techniques for correcting congenital and acquired heart diseases;
 
PEDIATRIC CARDIOLOGY:
 
• the use of new techniques of interventional catheterisation in congenital heart diseases;
• non-surgical closure of atrial septal defects with the use of the Amplatzer Septal Occluder;
• non-surgical closure of atrial septal defects with the use of CardioSeal/Starflex implants;
• non-surgical closure of post-infarction ventricular septal defects with the use of the Amplatz implant;
• the development of children with TGA operated in the neonatal period with the Jatene method
• the usefulness of heart rate variability assessment in patients with aortic insufficiency;
• the usefulness of 24-h monitoring of arterial blood pressure, stress test and dobutamine stress echocardiography in evaluating coarctation results in children;
• atrial septal defect – comparison of cardiosurgical and interventional treatment results;
• aortic coarctation – diagnosis, treatment, usefulness of the dobutamine test;
 
 CARDIAC SURGERY:
 
• acquired heart diseases – minimally invasive cardiac surgery, especially mitral and tricuspid valve repair procedures and aortic valve reconstruction – leading experience in Poland;
• treatment of the coronary disease and its complications (mitral and post-infarction insufficiency, post-infarction left ventricular aneurysm) – minimally invasive OPCAB, MIDCAB/TECAB, hybrid surgery, experimental and clinical research into surgical remodelling of the post-infarction damaged heart, preclinical research into the use of stem cells in patients with severe post-infarction cardiomyopathy, no revascularisation possibility and with permanent heart damage;
• aortic aneurysm – aortic aneurysm surgery preserving the patient’s own valve, hybrid operations and endovascular procedures in aortic aneurysms;
• congenital heart diseases - a full range of surgical procedures in congenital heart diseases in newborns and children below 18 years of age, the use of ECMO in saving newborns with severe circulatory and respiratory failure and older children with severe life-threatening circulatory and respiratory failure;
• surgical treatment of atrial fibrillation and surgical ablation
• heart failure, heart transplantation in adults and children, mechanical circulatory assistance, especially early-, mid- and long-term support with the Religa pneumatic device and the HEARTWARE axial-flow ventricular assist device.
• acute and chronic circulatory and respiratory failure in adults and children; lung transplantation;
 
DIABETOLOGY:
 
• the pathogenesis of diabetes;
• the pathogenesis of diabetic complications;
• the genetics of diabetes and its complications;
• optimisation of anti-hyperglycaemic therapy depending on diabetes stage and the coexistence of late complications.
 
Between 2007 and 2011, the Centre generated 208 articles published in journals of the ISI Master Journal List, with a combined IF = 443,4.
 
 
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